ACDF with a PEEK cage clinically provides a good outcome with minor donor site morbidity despite unsatisfactory radiological findings―A prospective cohort study of a PEEK cage in stand-alone usage―


Koichiro Okuyama1), Naohisa Miyakoshi2), Hiroshi Sasaki1), Tadato Kido1), Yoichi Shimada2)

1) Department of Orthopedic Surgery, Akita Rosai Hospital, Akita City, Japan
2) Department of Orthopedic Surgery, Akita University School of Medicine, Akita City, Japan


Study Design: A prospective cohort study was conducted on patients with anterior cervical decompression and fusion (ACDF) with a polyetheretherketone cage (PEEKc).
Background: Advantages of a PEEKc have been proposed in the study. However, benefits of using a PEEKc in ACDF are still controversial.
Objective: To investigate the advantages of a PEEKc in ACDF.
Materials and Methods: A total of 27 patients was enrolled in the study. The mean age of patients was 55±10 years (mean±standard deviation). The mean duration of symptoms was 17±21 months. Surgery was conducted at C3/4 in 1, C4/5 in 3, C5/6 in 11, C6/7 in 9, C7/T1 in 2, and C5/6/7 in 1 patient. The mean follow-up period was 2.1±1.3 years. Clinical outcomes were analyzed by the Japanese Orthopedic Association Scores (JOA scores) and its recovery rate. Perioperative complications were also investigated. Radiologically, studies were conducted on interbody lordotic angle (IBLA), interbody height (IBH), and bone fusion rates.
Results: The JOA score was 14.7±1.4 preoperatively and 16.3±1.3 at the final follow-up. A significant improvement was observed (p<0.05). The mean recovery rate of JOA scores was 74.0±25.0%. The preoperative IBLA was 0.5±6.1°. The mean IBLA at the final follow-up was 1.9±5.6°. The preoperative IBH was 34.2±3.5 mm. The mean IBH at the final follow-up was 34.3±3.5 mm. No significant improvement in IBLA and IBH was observed. A complete union rate at 1 year and 2.3 years (range, 2.0-6.0) after surgery was 29% (8/28 segments) and 61% (11/18 segments). No major complications were observed.
Conclusions: Despite an unsatisfactory bone union rate and no significant improvement in IBLA and IBH at the final follow-up, ACDF with a PEEKc clinically provided a stable outcome with less surgical invasion and minor donor-site morbidity.

Released: July 27, 2017; doi: